KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK8
All Species:
22.12
Human Site:
S484
Identified Species:
37.44
UniProt:
Q86SG6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86SG6
NP_835464.1
692
74806
S484
L
G
T
R
E
S
H
S
C
P
Q
Q
V
P
M
Chimpanzee
Pan troglodytes
XP_511801
843
90571
S635
L
G
T
R
E
S
H
S
C
P
Q
Q
V
P
M
Rhesus Macaque
Macaca mulatta
XP_001106986
781
84378
S573
L
G
T
R
E
S
H
S
C
P
Q
Q
V
P
M
Dog
Lupus familis
XP_548291
727
78319
S519
L
G
T
R
E
S
H
S
C
P
Q
Q
V
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q91ZR4
698
75246
N490
L
G
T
R
E
S
H
N
C
P
Q
Q
V
P
V
Rat
Rattus norvegicus
NP_001099274
698
75236
N490
L
G
T
R
E
S
H
N
C
P
Q
Q
V
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512532
832
89432
S468
L
G
T
R
E
S
H
S
C
P
Q
P
V
P
V
Chicken
Gallus gallus
XP_415822
728
79098
N490
L
G
T
L
E
C
H
N
S
P
Q
Q
V
A
V
Frog
Xenopus laevis
Q7ZZC8
944
104521
Y503
L
D
S
E
D
D
V
Y
S
P
Q
K
V
E
V
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
N491
L
A
T
Q
D
S
H
N
C
P
Q
Q
V
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_490968
998
111830
T730
I
F
G
R
N
D
N
T
E
L
G
L
G
N
S
Sea Urchin
Strong. purpuratus
XP_001201534
446
48490
S268
L
Q
V
S
I
G
R
S
Q
K
T
G
V
T
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
I428
K
T
S
F
L
H
Q
I
N
S
P
D
V
S
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
N565
T
R
S
R
P
S
L
N
S
Q
Q
N
S
N
V
Conservation
Percent
Protein Identity:
100
75.4
87
88.8
N.A.
93.5
93.4
N.A.
68.7
76.9
24.7
73.8
N.A.
N.A.
N.A.
23.2
38.2
Protein Similarity:
100
76.9
87.8
91
N.A.
96.4
95.4
N.A.
74
85.1
39.5
85.2
N.A.
N.A.
N.A.
37.8
50.8
P-Site Identity:
100
100
100
93.3
N.A.
86.6
93.3
N.A.
86.6
60
26.6
60
N.A.
N.A.
N.A.
6.6
20
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
93.3
73.3
53.3
86.6
N.A.
N.A.
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
N.A.
21.7
Protein Similarity:
N.A.
N.A.
N.A.
44
N.A.
37.1
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
8
0
0
58
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
15
15
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
8
58
0
0
0
8
0
0
0
0
8
0
% E
% Phe:
0
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
58
8
0
0
8
0
0
0
0
8
8
8
0
0
% G
% His:
0
0
0
0
0
8
65
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
0
8
0
0
8
0
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% K
% Leu:
79
0
0
8
8
0
8
0
0
8
0
8
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
43
% M
% Asn:
0
0
0
0
8
0
8
36
8
0
0
8
0
15
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
72
8
8
0
43
0
% P
% Gln:
0
8
0
8
0
0
8
0
8
8
79
58
0
0
0
% Q
% Arg:
0
8
0
65
0
0
8
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
22
8
0
65
0
43
22
8
0
0
8
22
8
% S
% Thr:
8
8
65
0
0
0
0
8
0
0
8
0
0
8
0
% T
% Val:
0
0
8
0
0
0
8
0
0
0
0
0
86
0
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _